The BEES Lab, DESE, IISc focuses on developing microchip-based system solutions for screening, diagnostic, and therapeutic applications in neuroscience and neurophysiology. The group develops single and multi-shank silicon microneedles integrated with microelectrodes and related signal conditioning modules to record neural biopotentials and signals and electrical stimulation of deep brain regions. These microneedle-based systems find applications in further understanding stroke, the efficacy of anti-epileptic drugs, and therapeutic interventions for Parkinson’s disease. To record the surface biopotentials and sub-dural signals of the brain, such as the electrocorticogram (ECoG), the group develops flexible devices with biocompatible materials with recording electrodes at microscale resolution. These devices are being tested on rat animal models to evaluate their robustness in neural recording and stimulation. The group also focuses on developing wearable headbands for screening for development deficits such as auditory cognition in neonates by recording and analyzing event-related potentials such as the cortical evoked potential.

Faculty: Hardik J Pandya, DESE